A Russian “guided bomb” has hit a blood transfusion centre in north-eastern Ukraine, killing two people and injuring four, Ukrainian officials say.
Volodymyr Zelensky posted an image of the building on fire as a result of Saturday night’s attack around Kupiansk, in the Kharkiv region.
“This war crime alone says everything about Russian aggression,” he said.
Russia has not commented. It has previously denied all allegations of targeting civilians – or war crimes.
The city of Kupiansk and nearby settlements were seized by Russian troops in the first few days of Moscow’s full-scale invasion of Ukraine, launched in February 2022.
The area was liberated during a Ukrainian counter-offensive last September, but comes under missiles and shelling daily.
In a post on social media, Mr Zelensky described the perpetrators as “beasts”.
“Defeating terrorists is a matter of honour for everyone who values life,” he added.
Mr Zelensky did not give details of the casualties. But local officials later posted the same image adding details about the attack on what they described as a non-residential building.
President Zelensky also said that on Saturday Russia separately carried out a missile attack, targeting an aeronautical company run by group Motor Sich in the western Khmelnytskyi region.
On Sunday, Russia’s air defences destroyed a drone as it approached Moscow, the city’s mayor, Sergei Sobyanin, said.
Last week, an office block on a Moscow skyscraper was hit two days in a row by Ukrainian drones, Russian authorities said.
Ukraine has not publicly admitted carrying out such attacks.
Moscow has also accused Ukraine on Saturday of hitting a Russian tanker with 11 crew members in the Black Sea – the second such sea drone attack in as many days.
Russian maritime officials said the engine room of the Sig tanker was damaged in the attack in the Kerch Strait. No-one was injured.
The Kerch Strait connects the Black Sea and the Sea of Azov, separating Crimea – Ukraine’s peninsula annexed by Moscow in 2014 – and Russia’s Taman peninsula.
Ukraine has not publicly commented. But a Ukrainian security service source told the BBC a sea drone had been used.
In another development, the Chonhar road bridge linking mainland Ukraine to Crimea was hit by a Ukrainian missile strike on Sunday, according to Russia’s RIA news agency.
This is the second time Ukrainian missiles have hit the bridge after an earlier attack in June forced it to close for repairs.
Moscow-installed Kherson regional governor Vladimir Saldo wrote on Telegram that another small bridge, connecting the port city of Henichesk and the narrow Arabat Spit on Crimea’s north-east coast, had been shelled.
A civilian driver was hurt and a gas pipeline was damaged, leaving 20,000 people without gas.